I’m pretty sure Azure Sphere used Pluton to do encryption for SSL. I don’t have any numbers, but one of the goals of Pluton was to accelerate crypto operations. But this was for a microcontroller context so I’m not sure about desktop/laptop class performance.
I don’t think pluton was used for disk or memory encryption, in Azure Sphere but I believe the possibility was discussed.
I’m afraid I don’t have anything more than speculation for the rest.
On desktops and laptops, will this device have a hardwired user-presence sensor, like Yubikeys do?
Would this device be performance-oriented enough to, for example, terminate SSL? I gather TPMs can, but only unhelpfully slowly [1]
Would it be performance-oriented enough to perform disk encryption? What about memory encryption?
[1] https://blog.habets.se/2012/02/Benchmarking-TPM-backend-SSL....