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Psilocybin reduced depression symptoms as much as leading antidepressant (2021) (massivesci.com)
31 points by dp-hackernews on May 3, 2025 | hide | past | favorite | 7 comments


More recent than this article have been failed clinical trials of psychedelics. Turns out forcing people chemically into a hallucinatory state isn’t that effective. To the point of this older article it seems that existing therapies are probably not the effective either.

So the search should be for therapies that surpass existing ones.


It's pretty bizarre the state that modern pharmaceutical psychiatry has reached. We literally have an FDA approved regimin of snorting ketamine to treat depression here in the US now (Spravato). Those ads are beyond dystopian: https://www.youtube.com/watch?v=FmhuerarE7I


Ad aside, what's wrong with that? Ketamine is proving to be extremely effective at treating depression


> forcing people chemically into a hallucinatory state

can you show evidence of any people being forced to do anything at all ?


You misunderstand. The body does not naturally hallucinate. To get it to do so requires overriding (forcing) the normal functions against their usual behavior with chemicals.


  >  The body does not naturally hallucinate
never?


More recent than those failed ones are successful ones tho.




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